The drug Tofranil belongs to a group of tricyclic antidepressants. It has antidepressant, antidiuretic, anxiolytic and analgesic effects. And also it has a strong sedative, peripheral and central anticholinergic effect.
The drug is used to treat depression (endogenous, menopause, alcohol), nocturnal enuresis in children, chronic pain associated with cancer, post-traumatic neuropathy, narcolepsy. Active ingredient of the drug is imipramine. Release form – pills or ampoules of 2ml.
The drug Tofranil is taken by mouth, in the initial stage of treatment, the dosage is 0,025 – 0,050 grams and then it gradually increases to 0.25 – 0.30 g. Initial intramuscular dose is 0,025 g several times a day, then the dose is gradually increased of 3-4. At the beginning of the treatment the sedative effect of the drug dominates.
Use of the drug Tofranil can reduce motor inhibition, improve your mood and normal sleep. Agitation and depressive symptoms are reduced among patients with anxiety and depression. Analgesic effect is due to changes in the concentration of serotonin in the central nervous system.
Premature discontinuation of the medication can lead to the resumption of the disease. It is not recommended to prescribe the effective drug Tofranil for children under the age of twelve.